DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage (1 of 2)

Caption

The energy generators in cells, mitochondria, have their own genetic material (green circles) which is maintained by a repair toolkit (red circle) unraveled in this study. This material relates to a paper that appeared in the April 28, 2017, issue of Science Advances, published by AAAS. The paper, by S.-C. Chiang at University of Sheffield in Sheffield, UK, and colleagues was titled, "Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage."

Credit

[Credit: Nora and Sherif El-Khamisy]

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