Muscle Deterioration in a Mouse Model of Duchenne Muscular Dystrophy (IMAGE)

Rockefeller University Press

Muscle Deterioration in a Mouse Model of Duchenne Muscular Dystrophy

Caption

A new study in the Journal of Cell Biology describes how increased production of the microRNA miR-21 leads to progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy. Muscle from an aged muscular dystrophy model mouse (left) contains large collagen deposits (red), but these are reduced when miR-21 is inhibited (right).

Credit

Ardite, E., et al.

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