New Microscope Peers at Subcellular Gears in Action (1 of 8) (IMAGE)

American Association for the Advancement of Science (AAAS)

New Microscope Peers at Subcellular Gears in Action (1 of 8)

Caption

T cell is expressing mEmerald-Lifeact (orange) approaching a target cell expressing a plasma membrane marker fused to tagRFP (blue), as seen from the side (top) and from the viewpoint of the APC (bottom). Initial contact (t=80 s). The two cells, after the formation of a mature immunological synapse (t=200 s). These data represent three time points from a 4-D, two-color data set spanning 400 time points. Scale bars, 4.0 micrometers (top), 5.0 micrometers (bottom). This material relates to a paper that appeared in the 24 Oct. 2014 issue of Science, published by AAAS. The paper, by B.-C. Chen at Howard Hughes Medical Institute in Ashburn, VA, and colleagues was titled, "Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution."

Credit

[Credit: Betzig Lab, HHMI]

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.