Pseudomonas Bacteria Better Harness Their Fuel Source, Driving Lung Infections in Cystic Fibrosis (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Pseudomonas Bacteria Better Harness Their Fuel Source, Driving Lung Infections in Cystic Fibrosis (1 of 2)

Caption

Human monocyte cell line infected with Pseudomonas aeruginosa (PA, cyan) and intracellularly stained for CFTR (cystic fibrosis transmembrane conductance regulator, green), PTEN (phosphatase and tensin homolog, red) and cell nuclei (blue). CFTR and PTEN are in proximity in Pseudomonas aeruginosa infection. This material relates to a paper that appeared in the Jul. 3, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by S.A. Riquelme at Columbia University in New York, NY; and colleagues was titled, "CFTR-PTEN-dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection."

Credit

[Credit: Pictures obtained by Dr. Sebastian A. Riquelme and Dr. Alice Prince at Columbia University, New York, USA.]

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