A Novel Human Stem Cell-based Model of ALS Opens Doors for Rapid Drug Screening (IMAGE)

Salk Institute

A Novel Human Stem Cell-based Model of ALS Opens Doors for Rapid Drug Screening

Caption

Top: When motor neurons (shown in red) are grown in the presence of defective astrocytes their numbers plummet. Bottom: Treating the cultures with apocynin, a powerful anti-oxidant, dramatically increases the survival of motor neurons. All cells' nuclei are labeled blue and neurons are shown in green. Right panel: Only motor neurons are shown.

Credit

Courtesy of Dr. M. Carol Marchetto, Salk Institute for Biological Studies

Usage Restrictions

News media reproduction to illustrate this story permitted with proper attribution as provided above. For one time use only.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.