Key Roles of Two <i>Plasmodium</i> Asparyl Proteases (IMAGE)

Université de Genève

Key Roles of Two <i>Plasmodium</i> Asparyl Proteases

Caption

This study identifies the key roles of two Plasmodium asparyl proteases , Plasmepsins IX and X that are crucial for malaria parasites entry and exit from the infected host cells Remarkably, a peptidomimetic inhibitor of theses two proteases exhibits a potent preventive, therapeutic, and transmission-blocking activity against malaria through the mosquitoes.

Credit

The picture is modified from Sturm and Hueussler, Med Microbiol Immunol (2007) 196:127-133 and designed by Cygny Malvar.

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