Graphical Abstract (IMAGE) Kanazawa University Caption SUCLA2 gene is frequently involved in the deletion of RB1 gene region, which occurs in 10 - 30 % of advanced prostate cancers. SUCLA2 deletion gives rise to a metabolic vulnerability. By screening chemical compounds, thymoquinone appeared to selectively kill SUCLA2-deficeint prostate cancer cells. Credit Kanazawa University Usage Restrictions The image may only be used with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.