Spindle Assembly Key to Chromosome Errors in Human Eggs (2 of 6) (IMAGE)

American Association for the Advancement of Science (AAAS)

Spindle Assembly Key to Chromosome Errors in Human Eggs (2 of 6)

Caption

Polar body extrusion in a human oocyte (Actin in cyan; Chromosomes in magenta; Microtubules in grey). This material relates to a paper that appeared in the June 5, 2015 issue of Science, published by AAAS. The paper, by Zuzana Holubcova at the Medical Research Council in Cambridge, UK, and colleagues was titled, 'Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes.'

Credit

[Credit: Zuzana Holubcova and Melina Schuh, MRC Laboratory of Molecular Biology]

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