Shutting Down Depression (IMAGE)

Rockefeller University

Shutting Down Depression

Caption

Experiments confirmed the molecule p11 (green) increases the receptor mGluR5's (red) presence on a cell's surface. This change amplifies sensitivity to certain signals--including those that promote depression--among certain neurons. The new antidepressants appear to interfere with this process.

Credit

Laboratory of Molecular and Cellular Neuroscience at The Rockefeller University/Molecular Psychiatry

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