New Human Neurons from Adult Cells Right There in the Brain (VIDEO)

Cell Press

Caption

This is a direct observation of neuronal reprogramming of PDGFR-sorted pericyte-derived cells from the adult human brain by continuous live imaging in culture. Note the change in morphology of a cell coexpressing Sox2 and Mash1 (blue arrow) during reprogramming. Postimaging immunocytochemistry for III-tubulin (white) confirms the neuronal identity of the reprogrammed cell at the end of live imaging.

Credit

<i>Cell Stem Cell</i>, a Cell Press Journal, Karow et al.

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