A Probiotic Synthetic Biology Approach against the Cholera Pathogen. (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

A Probiotic Synthetic Biology Approach against the Cholera Pathogen.

Caption

This plate assay shows how normal L. lactis bacteria (top row) can suppress the growth of V. cholera (bottom row). Normal L. lactis bacteria (upper left circle) acidify the medium around them (yellow color) and hinder V. cholerae (lower left circle) from growing in this area. A L. lactis mutant strain unable to acidify the medium (middle upper circle) has lost its acidifying ability and cannot suppress the pathogen anymore, whereas a repaired mutant L. lactis strain (upper right circle) both abilities again.

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Wyss Institute at Harvard University

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