Generation of piRNAs (IMAGE)

European Molecular Biology Laboratory

Generation of piRNAs

Caption

In germline cells PIWI proteins silence the RNA from jumping genes by cutting them in sequences of ~30 nucleotides that will become piRNAs. These new piRNAs bind to a nuclear PIWI protein to repress the expression of the jumping gene in the nucleus.

Credit

Ramesh Pillai/EMBL

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