Preclinical BPD (IMAGE)

Cincinnati Children's Hospital Medical Center

Preclinical BPD

Caption

The top two confocal microscopic images in this panel show underdeveloped pulmonary capillary networks in the lung of a laboratory mouse over exposed to oxygen (hyperpoxia) to mimic bronchopulmonary dysplasia, a condition that disrupts lung development in premature babies. The bottom two images show increased capillary density after a mouse with hyperpoxia was treated with c-KIT+ endothelial progenitor cells, a potential cell-based therapy reported by researchers in the American Journal of Respiratory and Critical Care Medicine.

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Cincinnati Children's Hospital

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