HLO Magnified (IMAGE) Cincinnati Children's Hospital Medical Center Caption This confocal microscopic image shows a tiny bioengineered human liver organoid grown in the lab with pluripotent stem cells. The mini-organ is accumulating inflammation and fat lipids (bluish bubble-like shapes), which are hallmarks of fatty liver and Wolman disease. The ability to closely mimic naturally occurring human liver disease in a research laboratory allowed researchers in the U.S. and Japan to determine underlying disease biology and search for much-needed new treatments, they report in Cell Metabolism. Credit Cincinnati Children's Usage Restrictions Please credit Cincinnati Children's License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.