Next-Generation Immunotherapy Offers New Hope for Beating Brain Cancer (IMAGE)
Caption
The researchers induced a specific type of cell death in brain cancer cells from mice. The dying cancer cells were then incubated together with dendritic cells, which play a vital role in the immune system. The researchers discovered that this type of cancer cell killing releases 'danger signals' that fully activate the dendritic cells. "We re-injected the activated dendritic cells into the mice as a therapeutic vaccine", Professor Patrizia Agostinis explains. "That vaccine alerted the immune system to the presence of dangerous cancer cells in the body. As a result, the immune system could recognize them and start attacking the brain tumor."
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©KU Leuven Laboratory of Cell Death Research & Therapy - Dr. Abhishek D. Garg
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