Candidate Cancer Drug Triggers Stress to Kill Solid and Blood Cancer Cells (1 of 3) (IMAGE)

American Association for the Advancement of Science (AAAS)

Candidate Cancer Drug Triggers Stress to Kill Solid and Blood Cancer Cells (1 of 3)

Caption

ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. This material relates to a paper that appeared in the Feb. 16, 2016 issue of Science Signaling, published by AAAS. The paper, by C.L.B. Kline at Penn State College of Medicine in Hershey, PA, and colleagues was titled, "ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases."

Credit

Oncoceutics, Inc.

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