Diazoxide Prevents Mitochondrial Damage in Spinal Cord After Ischemia-Reperfusion Injury (IMAGE)

American Journal of Pathology

Diazoxide Prevents Mitochondrial Damage in Spinal Cord After Ischemia-Reperfusion Injury

Caption

Transmission electron micrograph demonstrating diazoxide-mediated prevention of mitochondrial membrane damage and swelling in rabbit spinal cord after ischemia-reperfusion injury (magnification, x12,500). SCI, spinal cord ischemia; DZ, diazoxide. Copyright the American Society for Investigative Pathology.

Credit

Roseborough G, Gao D, Chen L, Trush MA, Zhou S, Williams GM, Wei C: The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord. Am J Pathol 2006 168:1443-1451.

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