Tamping Down a Terrible Trio in Eye Melanoma (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

Tamping Down a Terrible Trio in Eye Melanoma (1 of 1)

Caption

Caption: A cartoon showing the crystal structure of the asymmetric unit of TrioC, which was linked to some forms of cancer. This material relates to a paper that appeared in the Feb. 19, 2019, issue of Science Signaling, published by AAAS. The paper, by S.J. Bandekar at University of Michigan in Ann Arbor, MI; and colleagues was titled, "Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential."

Credit

S.J. Bandekar <em>et al., Science Signaling</em> (2019)

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