Comparison between liver biopsies and in vitro differentiated cells. (IMAGE)
Caption
In the upper panel, liver biopsies from a healthy (left) donor and an NAFLD patient (left) are shown. Huge clear vacuoles represent lipid droplets (Wruck et al, 2017). In the lower panel pictures of in vitro differentiated HLCs without fat treatment (left) and with fat induction (right) are shown (Graffmann et al, 2020). Cells were stained with Bodipy (green) to visualize fat and with PLIN2 (red) to visualize proteins covering the lipid droplets.
Credit
Dr. Nina Graffmann, University Hospital Duesseldorf
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