UvrD. (IMAGE)

University of Illinois Grainger College of Engineering

UvrD.

Caption

The DNA repair helicase UvrD can exist in an "open" (green, blue, cyan, and gray colored protein, upper right) or "closed" (middle) conformation. An instrument combining optical traps (red cones) and a single-molecule fluorescence microscope (green) is used to measure directly the relationship between these two structural states and their respective functions on DNA.

Credit

Matt Comstock, University of Illinois at Urbana-Champaign

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