Gene Editing Protein Efficiently "Skims" Over Irrelevant Targets (1 of 2) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

3-dimensional movie of Cas9 particles searching within a mammalian cell nucleus, with a 2- dimensional x,y-projection to the right. Bright white dots indicate binding events, and red flashes indicate freely diffusing particles. This material relates to a paper that appeared in the Nov. 13, 2015 issue of Science, published by AAAS. The paper, by S.C. Knight at University of California, Berkeley in Berkley, CA, and colleagues was titled, 'Dynamics of CRISPR-Cas9 genome interrogation in living cells.'

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AAAS, UC Berkeley/HHMI

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