Muscular Dystrophy Insights (IMAGE)

American Association for the Advancement of Science (AAAS)

Muscular Dystrophy Insights

Caption

This image shows separation of the sarcolemma and basal lamina in skeletal muscle caused by the aberrant modification of alpha-dystroglycan in a myodystrophic mouse model. This image relates to an article that appeared in the January 1 issue of Science, published by AAAS. The study, by Dr. T. Yoshida-Moriguchi of the Howard Hughes Medical Institute in Iowa City, Iowa, and colleagues, was titled, "0-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Bindings."

Credit

Image courtesy of David E. Muirhead, Takako Yoshida-Moriguchi and Kevin P. Campbell

Usage Restrictions

Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</I> for permission.

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