Transgenic zebrafish embryos (IMAGE)

Aarhus University

Transgenic zebrafish embryos

Caption

Fluorescently labelled 70 nm SiO2 nanoparticles were injected into the bloodstream of 3 days old transgenic zebrafish embryos and live-imaged at 3 min after the injection. The insets show schematics for the two conditions tested: control nanoparticles with a corona of endogenous proteins (orange) and nanoparticles with a pre-formed corona of fetal bovine serum (FBS) proteins (blue) and additional endogenous proteins. Control nanoparticles are rapidly captured by macrophages, while the nanoparticles with a non-self biological identity are effectively sequestered by scavenger endothelial cells.

Credit

Yuya Hayashi. Adapted from Mohammad-Beigi et al. (2020) ACS Nano. Copyright 2020 American Chemical Society

Usage Restrictions

Image may be used only to illustrate the research described in the accompanying release

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.