TCR-pMHC Recognition -- through the Looking Glass (IMAGE)

Monash University

TCR-pMHC Recognition -- through the Looking Glass

Caption

The image shows a brightly colored canonical interaction between TCR and pMHC which is conducive to signal transduction. The faded mirror image shows a reversed TCR-pMHC interaction which is unable to support signal transduction and thus T cell activation.

Credit

Created by Dr. Erica Tandori (Rossjohn lab

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