Working Mouse Eggs Made From Stem Cells (4 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

Working Mouse Eggs Made From Stem Cells (4 of 4)

Caption

(Upper left) These are GV oocytes isolated from reconstituted ovaries with PGCLCs from iPSCs. (Upper middle) In vitro maturated MII oocytes from the GV oocytes from iPSC-derived PGCLCs. (Upper right) These are offspring from oocytes from iPSC-derived PGCLCs with black eyes indicted by white arrows. (Bottom left) Adult offspring from oocytes from iPSC-derived PGCLCs. (Bottom right) Female offspring from oocytes from iPSC-derived PGCLCs were fully fertile. This image relates to a paper that appeared in the Oct. 4, 2012, issue of Science Express, published by AAAS. The paper, by Mitinori Saitou at Kyoto University in Kyoto, Japan, and colleagues was titled, "Offspring from Oocytes Derived from in vitro Primordial Germ Cell-like Cells in Mice."

Credit

Courtesy of Katsuhiko Hayashi

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