Compound Found in Chinese Medicinal Herb Zaps Inflammation (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Compound Found in Chinese Medicinal Herb Zaps Inflammation (1 of 2)

Caption

This image features a maximum intensity projection showing neutrophil tracks in dimethyl sulfoxide-treated (as opposed to Tanshinone IIA-treated) larvae from six to eight hours post-injury. Neutrophils are labeled with the photoconvertable protein Kaede. Red tracks represent neutrophils that were present at the wound at six hours post injury and were photoconverted from green to red fluorescence. This image relates to a paper that appeared in the Feb. 26, 2014, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. A.L. Robertson at the University of Sheffield in Sheffield, UK, and colleagues was titled, "A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism."

Credit

Image courtesy of Anne L. Robertson

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