Treatment Resistant Leukemia (IMAGE)
Caption
This image shows treatment-resistant chronic myeloid leukemia cells (CML) in laboratory mouse models. Researchers report March 20 in Nature Medicine that two signaling proteins in certain cancer cells make them resistant to chemotherapy treatment. Inhibiting these proteins combined with chemotherapy eradicated CML- and residual disease cells that can refuel the disease -- in laboratory models of leukemia.
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Cincinnati Children's
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