Treatment Resistant Leukemia (IMAGE) Cincinnati Children's Hospital Medical Center Caption This image shows treatment-resistant chronic myeloid leukemia cells (CML) in laboratory mouse models. Researchers report March 20 in Nature Medicine that two signaling proteins in certain cancer cells make them resistant to chemotherapy treatment. Inhibiting these proteins combined with chemotherapy eradicated CML- and residual disease cells that can refuel the disease -- in laboratory models of leukemia. Credit Cincinnati Children's Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.