diagram (IMAGE) The Chinese University of Hong Kong Caption Prpf19 degrades the disease protein of SCA3 and alleviates its toxicity. Exoc7 protein restrains Prpf19 from functioning the degradation, causing it to lose its beneficial effects on SCA3. Credit CUHK Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.