Novel DNA Repair Mechanism (IMAGE)

Lomonosov Moscow State University

Novel DNA Repair Mechanism

Caption

Estimated structure of the nucleosomal DNA loops, which are temporarily formed during transcription of chromatin containing intact DNA by RNA polymerase II (Pol II). In the presence of a single-strand DNA break, the loop structure likely changes, preventing rotation of the RNA polymerase along the DNA helix (orange arrow).

Credit

Nadezhda S. Gerasimova et al

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