RNA Binding Protein Supports Harmful Tau Buildup in Alzheimer's Disease (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

RNA Binding Protein Supports Harmful Tau Buildup in Alzheimer's Disease (1 of 1)

Caption

Human kidney cells that lacked the MSUT2 protein expressed more of the disease-causing human tau protein (green). This material relates to a paper that appeared in the Dec. 18, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by J.M. Wheeler at Veterans Affairs Puget Sound Health Care System in Seattle, WA; and colleagues was titled, "Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain."

Credit

[Credit: J.M. Wheeler <i>et al., Science Translational Medicine</i> (2019)]

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