HIV Enzyme Structure (VIDEO) American Institute of Physics This video is under embargo. Please login to access this video. To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Caption When it binds an inhibitor drug, HIV reverse transcriptase is forced into an open state that cannot transcribe RNA to DNA though a single amino acid mutation can make the protein drug resistant. Credit G. Schauer/University of Pittsburgh Usage Restrictions This video may be used only with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.