Skin of Normal Mice (IMAGE)

PLOS

Skin of Normal Mice

Caption

This image shows skin of normal mice. IL-10 production by CD4+ T cells (green) following infection of the skin with Schistosoma mansoni cercariae, prevents excessive inflammation of the epidermis and dermis, and limits the influx of myeloid cells (CD11b+ (yellow); MHC-II+ (red)). IL-10 is triggered by commensal microorganisms that gain entry to the host during percutaneous infection with schistosome larvae infection, which subsequently sustains the production of IL-10.

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Mountford et al., CC-BY

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