Turn up the Noise to Treat HIV (VIDEO)
Caption
This is a time-lapse fluorescence microscopy movie of LTR-d2GFP polyclonal cells for 20 hours, 24 hours post-treatment with noise enhancer V1. The movie plays on a loop and displays 20 unique x-y locations sampled over time in a 4x5 array. Tracked single-cells are marked with a red dot for quality control and post-processing. For more information, please see the Supporting Online Material. This video relates to a paper that appeared in the 5 June, 2014, issue of Science Express, published by AAAS. The paper, by Roy Dar at Gladstone Institute of Virology and Immunology in San Francisco, Calif., and colleagues was titled, "Screening for noise in gene expression identifies synergistic drug cocktails."
Credit
[Video © Dar <i>et al., Science</i>/AAAS 2014]
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