Artist's Illustration (IMAGE)

World Scientific

Artist's Illustration

Caption

This is an artist's illustration of the microfluidic system for probing red blood cell (RBC) dynamic deformability and adhesion from whole SCD patient blood samples. Microfluidic system is composed of a Poly(methyl methacrylate) (PMMA) cover, a double sided adhesive (DSA) layer, and a glass slide base. Microfluidic channels are functionalized with fibronectin, which mimics the microvasculature wall in a closed system and can process whole blood. Adhered sickled RBCs deform in microfluidic channels in response to applied flow shear stress.

Credit

Credit: Grace Gongaware, Cleveland Institute of Art

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.