A Plier-Like Gripe (IMAGE)
Caption
Two activated STAT3 molecules surround DNA (center). Previously, efforts to interfere with STAT3's contribution to cancer have focused on interactions between the SH2 domains (yellow) at the tip of the pliers. Darnell and his team instead altered the linker domains (orange).
Credit
Laboratory of Molecular Cell Biology at The Rockefeller University/PNAS
Usage Restrictions
Image may be used only to illustrate the research described in the accompanying release.
License
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