Figure 3 (IMAGE) Waseda University Caption When Aurora B, PP2A, and SET function accurately as tension sensors, the maintained balance of phosphorylation at the kinetochore leads to precise chromosome alignment and segregation. However, the abnormal tension sensor leads to chromosome missegregation, thereby causing cancer and genetic diseases such as Down's syndrome. Credit Terada Laboratory, Waseda University Usage Restrictions Image may only be used with appropriate caption and credit to Terada Laboratory, Waseda University. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.