Examples of True-Positive, False-Positive, and False-Negative Assessments of NASH (IMAGE)
Caption
A and B, True-positive assessments in 58-year-old woman (A) and 52-year-old man (B) with high-risk NAFLD and associated NASH. CT images show hepatic enlargement, heterogeneously low-attenuation hepatic parenchyma, and surrounding ascites. Readers correctly identified NASH according to these imaging features. Readers also correctly identified fibrosis stage F3. C and D, False-positive assessments in 73-year-old woman (C) and 61-year-old woman (D) with high-risk NAFLD but without pathologic evidence of NASH. CT images show findings similar to A and B. Readers incorrectly identified NASH because of these imaging findings but correctly identified fibrosis stages F3 (C) and F4 (D). E, False-negative assessment in 56-year-old woman. CT image shows liver is not enlarged, heterogeneous, or low in attenuation, and ascites is not present. Both readers interpreted image as not showing findings indicative of NASH. However, NASH was diagnosed from surgical pathology.
Credit
American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR)
Usage Restrictions
Image may only be used with appropriate caption or credit.
License
Licensed content