Generation and Interpretation of Morphogen Gradients (IMAGE)

Cold Spring Harbor Laboratory

Generation and Interpretation of Morphogen Gradients

Caption

The front cover of "Generation and Interpretation of Morphogen Gradients" features a Drosophila embryo two hours after fertilization, with nuclei at the surface fluorescently labeled for Bicoid protein (green), Hunchback protein (red), and DNA (blue). The shallow Bicoid gradient generates a sharp Hunchback boundary (enlarged in the background), partitioning the embryo in half. This input/output relationship is quantitatively represented in the foreground (yellow); each dot specifies the Bicoid concentration (horizontal axis) and Hunchback concentration (vertical axis) measured in a single nucleus. Image courtesy of Thomas Gregor.

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Cold Spring Harbor Laboratory Press

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