A Safe and Established Drug Could Help Treat Neurodegenerative Disorders (3 of 5) (IMAGE)

American Association for the Advancement of Science (AAAS)

A Safe and Established Drug Could Help Treat Neurodegenerative Disorders (3 of 5)

Caption

A laser scanning image showing a region of brain tissue populated by mutant tau (white), protoplasmic astrocytes (red), microglia (green), and nuclei (blue) in the rTg4510 mouse. This material relates to a paper that appeared in the Mar. 27, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by I. Hernandez at University of California, Santa Barbara in Santa Barbara, CA; and colleagues was titled, "A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy."

Credit

Gabriel Luna and Israel Hernandez, Kosik Lab, Neuroscience Research Institute, UC Santa Barbara

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