Rat Tibia Micro CT Scan (IMAGE) Hokkaido University Caption Micro CT scan images of the tibia in three rat specimens. In the right image, a specimen given bisphosphonates without inhibiting the Siglec-15 protein shows signs of reduced growth (white arrows) as well as an overall rounder structure indicating malformation (yellow arrows) compared to the central image, in which Siglec-15 was inhibited. The left image shows a control group specimen. Credit Sato et al., <em>Bone</em>, November 2018 Usage Restrictions This image is copyrighted and can be used for reporting this press release if properly credited. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.