Chromatin Deregulation in Cancer (IMAGE) Cold Spring Harbor Laboratory Caption The image depicts six broad categories of chromatin regulatory mechanisms, which are all known to be altered via mutations in the pathogenesis of human cancer. Credit Figure adapted by Meredith Cassuto, Cold Spring Harbor Laboratory, from the cover of Epigenetics, 2nd ed., 2015, with permission from CSHL Press. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.