Model (IMAGE) University of Münster Caption Comparison between the normal TMEM16A protein and the mutated variant showing the truncating effect that leads to the loss of vast portions of the protein. This leads to severe structural alterations. Credit J. Park et al. 2020/ <i>Journal of Medical Genetics</i> Usage Restrictions Please use this picture only in connection with the press release. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.