Twisted Intramolecular Charge Shuttle (TICS) (IMAGE) Singapore University of Technology and Design Caption (a) Schematic illustration of the twisted intramolecular charge shuttle (TICS) mechanisms; 'D' and 'A' denote electron-donating and electron-accepting fragments, respectively. (b) Reaction mechanism of a TICS based GSH fluorescent probe, and confocal microscope images of HeLa cells stained with the probe and Hoechst 33342 (a nucleus stain with blue emissions). No red emissions were observed in cells that were pre-treated with 1 mM NMM to remove GSH, while intense red fluorescence was present in cells with GSH. Scale bar = 20 μm. Credit SUTD Usage Restrictions Image should be used with the appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.