Biochip Schematic (IMAGE)

University of Illinois Grainger College of Engineering

Biochip Schematic

Caption

Differential immuno-capture biochip schematic: 1. Ten microliters of blood is infused into the biochip. 2. Erythrocytes were lysed and the leukocytes were preserved using as custom-made lysing and quenching buffers get mixed with blood. 3. The leukocytes pass over co-planar platinum microfabricated electrodes and are counted. 4. Specific cell antibodies e.g. monoclonal CD4 T cell antibody is initially adsorbed on the capture chamber. CD4 T cells get captured as they interact with the antibodies in the chamber. 5. Remaining leukocytes gets counted again with second counter. The difference in the respective cell counts give the concentration of the cells captured.

Credit

Umer Hassan, University of Illinois

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