Genetically Engineered Antibodies Show Enhanced HIV-Fighting Abilities (IMAGE)
Caption
Antibodies generally attack a virus by binding with both of their "arms" to two of the spikes sticking up from the surface of the virus. Caltech researchers propose that HIV's low spike density makes it hard for antibodies to do this. The biologists engineered antibody-based molecules that can bind to a single HIV spike with both arms and showed that the new molecules are more than 100 times better than naturally occurring antibodies at binding to and neutralizing HIV.
Credit
Lance Hayashida/Caltech Marketing & Communications and the Bjorkman Laboratory/Caltech
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