Sonic Hedgehog Control of Brain Development (IMAGE)

University of Pennsylvania School of Medicine

Sonic Hedgehog Control of Brain Development

Caption

Comparison of expression of a reporter gene under the regulatory control of a wild type and mutant Shh brain enhancer - SBE2 (blue). Note that the reporter gene is expressed more fully from the wild type (WT) versus the mutant (Mut) Shh enhancer in the hypothalamus of a 10-day-old mouse embryo.

Credit

Douglas J. Epstein, University of Pennsylvania School of Medicine

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