Therapeutic Effect Of A Polysulfide Donor On A Murine Model For Endotoxin Shock (IMAGE)

Kumamoto University

Therapeutic Effect Of A Polysulfide Donor On A Murine Model For Endotoxin Shock

Caption

When lipopolysaccharide derived from E. coli was administered intraperitoneally in mice, the survival rate decreased to 20% after 96 hours in the untreated group. Treatment with a polysulfide donor 30 minutes after administration of lipopolysaccharide improved the survival rate to 90%. In the treatment group, they also found that the amount of cytokines, an indicator for inflammation, was greatly reduced.

Credit

Prof. Tomohiro Sawa

Usage Restrictions

This image may only be used in conjunction with the accompanying release, or stories written about the work described in the release with reference to the original work.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.