Drug Stalls Ribosome (IMAGE)

University of California - Berkeley

Drug Stalls Ribosome

Caption

Ribosomes lined up along pieces of messenger RNA extrude proteins that curl up once they emerge from the ribosome's internal tunnel. UC Berkeley and Pfizer scientists discovered that a small molecule (black T) can kink the growing protein inside the tunnel and stall its production while leaving general protein production unaffected.

Credit

Jamie Cate image.

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