CAS Scientists Discover BCAS2 Involved in Alternative mRNA Splicing in Spermatogonia and the Transition to Meiosis (IMAGE)

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CAS Scientists Discover BCAS2 Involved in Alternative mRNA Splicing in Spermatogonia and the Transition to Meiosis

Caption

Bcas2 is involved in pre-mRNA splicing in mouse spermatogenesis. (a) RNA-seq results showed that 245 genes are altered in alternative splicing forms in Bcas2 depletion mouse testis, including six spermatogenesis-related genes (Dazl, Hsf1, Ehmt2, Hmga1, Bcl2l11 and Cit). The aberrant splicing patterns in Dazl, Ehmt2 and Hmga1 were verified by RT-PCR (b) and quantitative RT-PCR (c).

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LI Lei

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