Learning 1 of Cancer's Tricks (IMAGE)

California Institute of Technology

Learning 1 of Cancer's Tricks

Caption

A computational model depicts a PFK1 enzyme with the sugar GlcNAc attached (left). Comparing this model to that showing PFK1 complexed to a molecule that activates the enzyme (right) suggests how addition of GlcNAc may inhibit enzymatic activity.

Credit

Caltech/Yi et al.

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